Jean-Marc Poudrel
"Le Poodle"
Post-Doctoral Fellow
(from France)
Qualifications
Grad.Dip.(Engineering)
@ National Chemistry
School of Montpellier
PhD @ University of
Montpellier II
|
|
Email: Jean-Marc.Poudrel@ucb-group.com
Research Project/Area
Synthesis of Inhibitors of the cis/trans Peptidyl-Prolyl Isomerase FKBP12 (FK506 Binding Protein) : Macrocyclic Peptidomimetics of the Immunosuppressant FK506 incorporating a Sulfoxide Unit as Transition State Mimic
Academic History
PhD at University of Montpellier II
Supervisor: Jean-Pierre Girard
Thesis: Synthesis and Structure-Activity Relationships of Cyclohexanic Compounds as New Leukotriene B4 Antagonists
Selected Publications
Synthesis and pharmacological profile of 1,3-disubstituted cyclohexanes
as leukotriene B4 antagonists, J.M. Poudrel, P. Hullot, A. Muller,
C. Bonne, J.C. Rossi & J.P. Girard, Bioorganic and Medicinal
Chemistry Letters, 1996, 6(19), 2349-2355.
Structure-activity relationships of new non aromatic leukotriene
B4 receptor antagonist, J.M. Poudrel, P. Hullot, J.P. Vidal,
J.C. Rossi & J.P. Girard, Prostaglandins, Leukotrienes & Essential
Fatty Acids, 1996, 55 (suppl. 1), 94.
Synthesis and Biochemical/Pharmacological Profile of the Novel
Leukotriene B4 Receptor Antagonist: Sodium
(1S*,3S*)-1-hydroxy-3-[(3R*S*,E)-3-hydroxy-7-phenyl-1-hepten-1-yl]-1-
cyclohexane acetate, P. Hullot, J.M. Poudrel, A. Muller, R. Escale,
J.C. Rossi, J.P. Girard & C. Bonne, Arzneimittel Forschung-Drug
Research, 1997, 47 (1), 51-58.
Synthesis and Structure Activity Relationships of New
1,3-Disubstituted cyclohexanes as Structurally Rigid Leukotriene B4
Receptor Antagonists, J.M. Poudrel, P. Hullot, J.P. Vidal, J.P.
Girard, J.C. Rossi, A. Muller, C. Bonne, V. Bezuglov, I. Serkov, P.
Renard & B. Pfeiffer, Journal of Medicinal Chemistry, 1999, 42 (26),
5289-5310.
|
